Monday, April 5, 2021

Face Masks Reduce Retinal Vessel Density

Who are you going to follow: The sociopath Fauci or scientists who ran tests on subjects wearing masks?

Anthony Fauci

From The Review of Optometry:

Since the beginning of the COVID-19 pandemic, face masks have become a part of people’s everyday lives when in public, including during exercise. Researchers decided to investigate whether mask wearing influences activities such as exercise and sought to determine the possible impact mask wearing has on retinal microvasculature.

In this study, 23 healthy young adults with different masks participated in a running test wherein speed was gradually increased until their heart rate reached 190 BPM. OCT angiography of the macula and optic nerve head were performed before and after the test to detect changes in retinal vessel density (VD). Participants were studied in three groups: volunteers without a mask, with a surgical mask and with an N95 mask.

Before exercise, the N95 group showed significantly reduced VD in the superficial plexus, except foveal VD, compared with unmasked subjects. After exercise, both masked groups showed significantly shorter maximum running time, lower oxygen saturation and lower perifoveal VD of SP compared with unmasked subjects.

The study concludes the use of an N95 mask reduced VD in the superficial plexus even under quiescent conditions, which might have clinical implications for protecting healthy workers and indoor manual labor workers from potential risks of retinal damage due to long-term mask use.

A notable finding was that, although only perifoveal VD in the superficial plexus showed significant reductions in mask-wearing groups after ICRT, heart rate reached 190 BPM significantly earlier and oxygen saturation was significantly lower upon completion of the exercise test during the use of surgical or N95 masks.

The authors found this notable because a previous study showed that surgical mask use significantly aggravated difficulty in breathing (dyspnea) during the six-minute walk test compared to the absence of a surgical mask during the test.

“Moreover, N95 and surgical masks might perform airflow restriction comparable to that of an elevation training mask, which has been used to simulate a hypoxic environment (similar to altitude training) for athletes,” the authors noted in their study. “Mask use has been shown to cause some adverse effects, including delayed cardiac-autonomic recovery from exercise, attenuated exercise ability, reduced awareness of sports injury, and hypoxemia. Our results indicate that the use of an N95 or surgical mask also might lead to a decline in exercise ability and earlier and stronger reductions of retinal VD in young adults.”

Because of this, the authors believe the public should use caution while exercising with a face mask, being mindful to take unmasked breaks when possible, and limit physical activities during mask wear.

The authors of the paper: 

Dihao Hua; Yishuang Xu; Peter Heiduschka; Wenliang Zhang; Xiao Zhang; Xiangbing Zeng; Xiangxiang Zhu; Tao He; Hongmei Zheng; Xuan Xiao; Yiqiao Xing; Zhen Chen; Changzheng Chen

The full paper:

Retina Vascular Perfusion Dynamics During Exercise With and Without Face Masks in Healthy Young Adults: An OCT Angiography Study

Don't forget, I had very early concerns about mask-wearing and even contacted OSHA:  Has OSHA Even Tested to Determine If Mask Wearing is Safe?


(ht Michael Edelstein)


  1. This test will have more credibility when it is re-run using mannequins.

  2. Thank you for this, RW. My 5 year old girl has exotropia and I need to share this study with her ophthalmologist.

    1. Fearing a threat to his/her license, you will hear that one study doesn't prove anything.

    2. Hehe no doubt, but I never let them off that easy :)